Ingredient exposition: ergothioneine (Ergothionine, EGT)

What the hell is that?

Ergothioneine (Ergothionine, known as EGT) is a naturally occurring sulphuric amino acid-type compound that was first found in rhesus.

But the most shocking thing about it is that the human body has a special "Occupant" protein!

What does that mean?

  • It's not an ordinary ingredient, it's an "essential nutrient" that the body needs.
  • Platoon, skin stem cells, highest concentration in immune cells
  • In 1909, it was only in 2017 that the FDA was identified as a "food supplement", and the ingredient boundary was on the eve of the outbreak.

💡 core efficacy resolution (why is it "super antioxidant agent")

1 antioxidant capability (70 times C)

This is the core of EGT's sales point, the lab data:

  • Clear free-base capability: 700 times VC
  • Clear single-linear oxygen capability: 400 times
  • Clearance of hydrogen peroxide: 200 times

Data support: A study published in Biochemic Journal shows that EGT significantly outperformed traditional antioxidant agents such as , C, VE, coenzyme Q10 in protecting cells from oxidation.

2x2 unique mitochondria DNA protection mechanism

EGT has three unique advantages:

  • Linear particle target: EGT accumulates on-line inner membrane, directly protecting linear particle DNA from oxidation
  • Recycled: EGT oxidized, theoretically repeated, unlike VC scrapped
  • Selective protection: automatic activation under oxidation pressure, "sleep" in normal condition, without disrupting normal physiological function
Common analogy: VC's like a firefighter. EGT's like a fire station.

Triple three. Activate the Nrf2 Road.

Nrf2 is a cell antioxidant stressed "total switch" protein.

  • Stability of Nrf2 protein to prevent degradation
  • Up and down antioxidant enzyme (SOD, GPx, HO-1)
  • In the long run, it's an old defense network.

Data support: In vitro experiments showed 0.1% SOD activity increased by 35% and HO-1 expression by 2.8 times after 24 hours of EGT treatment

Protection of skin stem cells

This is the top course of EGT's research:

  • Skin stem cells are the source of regenerative skin.
  • EGT sustains stem cell activity, slows ageing.
  • This means that EGT may improve skin state at its root, not just surface antioxidant

Ingredient

Practical applications in products

Ergothioneine applications in market products are growing rapidly:

  • Serum: Current most common form, EGT 0.1-0.5%
  • Eye cream: protection of vulnerable skin in the eye, EGT usually combined with acetyl hexaazine-3
  • Sun protection: EGT removes leaking free radicals and reduces light ageing as "sun protection back"
  • Ampoule: high concentration, consumer group for strong antioxidant
  • Repairing fine: repairing after medical art, EGT protected line + antioxidant
OEM Perspective: ergothioneine raw materials cost about 10-20% of the total formulation cost, which supports important high- and middle-end outlets. At present, the main suppliers include international vendors such as DSM, Tri-K and Croda.

• Guide to the selection and purchase of pits

  • See concentration: valid concentration requires ≥0.05 per cent, less than 0.01 per cent, which is largely unattractive (but the manufacturer does not usually mark specific concentration and recommends that ingredient tables be ranked)
  • Watching ranking: ingredient table, Ergothionine in front, concentration higher
  • See formulation stability: EGT is the most stable in a neutral environment and avoids strong acid/bracket products
  • See the combination of formulation: EGT+VC/ centella asiatica 苷/ ceramide, etc. multi-composed formulation, more effective
  • See packaging: EGT is sensitive to light and temperature and recommends the selection of packaging for good sealed products

Where's EGT?

Ergothioneine ingredient?
The QuickOEM R & D team is good at EGT formulation design, optimizing from stability to efficacy testing one-stop service to help you build the next generation of antioxidant best-selling product products.

Next edition of the forecast: EGT vs microbes fermented EGT, cost, efficacy, stability, 3D comparison, formulation division!

Other Organiser

This article is published by the QuickOEM Make-up OEM Smart Matching Platform. More makeup OEM knowledge, cosmetics contract manufacturing, skin protection private label, make-up customizationontent are available at the Knowledge Centre. If you need advice on OEM contract manufacturing, please contact 1814805760 or submit your request through an online request for quotation.

Keywords: OEM, EGT concentration selection, ergothioneine efficacy role, packaging, ergothioneine ingredient acquisition, Ergothionine, DSM, long-lived molecular skin protection, SOD, efficacy test, Aol, Croda, EGT, raw materials, EGT antioxidant protection, ingredient science pup, cosmetics ingredient resolution, make-up ingredient security, ingredient protection skin protection

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