Ingredient exposition: ergothioneine (Ergothionine, EGT)

What the hell is that?

Ergothioneine (Ergothionine, known as EGT) is a naturally occurring sulphuric amino acid-type compound that was first found in rhesus.

But the most shocking thing about it is that the human body has a special "Occupant" protein!

What does that mean?

  • It's not an ordinary ingredient, it's an "essential nutrient" that the body needs.
  • Platoon, skin stem cells, highest concentration in immune cells
  • In 1909, it was only in 2017 that the FDA was identified as a "food supplement", and the ingredient boundary was on the eve of the outbreak.

💡 core efficacy resolution (why is it "super antioxidant agent")

1 antioxidant capability (70 times C)

This is the core of EGT's sales point, the lab data:

  • Clear free-base capability: 700 times VC
  • Clear single-linear oxygen capability: 400 times
  • Clearance of hydrogen peroxide: 200 times

Data support: A study published in Biochemic Journal shows that EGT significantly outperformed traditional antioxidant agents such as , C, VE, coenzyme Q10 in protecting cells from oxidation.

2x2 unique mitochondria DNA protection mechanism

EGT has three unique advantages:

  • Linear particle target: EGT accumulates on-line inner membrane, directly protecting linear particle DNA from oxidation
  • Recycled: EGT oxidized, theoretically repeated, unlike VC scrapped
  • Selective protection: automatic activation under oxidation pressure, "sleep" in normal condition, without disrupting normal physiological function
Common analogy: VC's like a firefighter. EGT's like a fire station.

Triple three. Activate the Nrf2 Road.

Nrf2 is a cell antioxidant stressed "total switch" protein.

  • Stability of Nrf2 protein to prevent degradation
  • Up and down antioxidant enzyme (SOD, GPx, HO-1)
  • In the long run, it's an old defense network.

Data support: In vitro experiments showed 0.1% SOD activity increased by 35% and HO-1 expression by 2.8 times after 24 hours of EGT treatment

Protection of skin stem cells

This is the top course of EGT's research:

  • Skin stem cells are the source of regenerative skin.
  • EGT sustains stem cell activity, slows ageing.
  • This means that EGT may improve skin state at its root, not just surface antioxidant

Ingredient

Practical applications in products

Ergothioneine applications in market products are growing rapidly:

  • Serum: Current most common form, EGT 0.1-0.5%
  • Eye cream: protection of vulnerable skin in the eye, EGT usually combined with acetyl hexaazine-3
  • Sun protection: EGT removes leaking free radicals and reduces light ageing as "sun protection back"
  • Ampoule: high concentration, consumer group for strong antioxidant
  • Repairing fine: repairing after medical art, EGT protected line + antioxidant
OEM Perspective: ergothioneine raw materials cost about 10-20% of the total formulation cost, which supports important high- and middle-end outlets. At present, the main suppliers include international vendors such as DSM, Tri-K and Croda.

• Guide to the selection and purchase of pits

  • See concentration: valid concentration requires ≥0.05 per cent, less than 0.01 per cent, which is largely unattractive (but the manufacturer does not usually mark specific concentration and recommends that ingredient tables be ranked)
  • Watching ranking: ingredient table, Ergothionine in front, concentration higher
  • See formulation stability: EGT is the most stable in a neutral environment and avoids strong acid/bracket products
  • See the combination of formulation: EGT+VC/ centella asiatica 苷/ ceramide, etc. multi-composed formulation, more effective
  • See packaging: EGT is sensitive to light and temperature and recommends the selection of packaging for good sealed products

Where's EGT?

Ergothioneine ingredient?
The QuickOEM R & D team is good at EGT formulation design, optimizing from stability to efficacy testing one-stop service to help you build the next generation of antioxidant best-selling product products.

Next edition of the forecast: EGT vs microbes fermented EGT, cost, efficacy, stability, 3D comparison, formulation division!

Other Organiser

This article is published by the QuickOEM Cosmetic OEM Smart Matching Platform. More makeup OEM knowledge, cosmetics contract manufacturing, skin protection private label, make-up customizationontent are available at the Knowledge Centre. If you need advice on OEM contract manufacturing, please contact 1814805760 or submit your request through an online request for quotation.

Keywords: OEM, EGT concentration selection, ergothioneine efficacy role, packaging, ergothioneine ingredient acquisition, Ergothionine, DSM, long-lived molecular skin protection, SOD, efficacy test, Aol, Croda, EGT, raw materials, EGT antioxidant protection, ingredient science pup, cosmetics ingredient resolution, make-up ingredient security, ingredient protection skin protection

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